Cd4(+) T Cell Subsets during Virus Infection: Protective Capacity Depends on Effector Cytokine Secretion and on Migratory Capability

To analyze the antiviral protective capacities of CD4(+) T helper (Th) cell subsets, we used transgenic T cells expressing an I-A(b)–restricted T cell receptor specific for an epitope of vesicular stomatitis virus glycoprotein (VSV-G). After polarization into Th1 or Th2 effectors and adoptive transf...

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Detalhes bibliográficos
Main Authors: Maloy, Kevin J., Burkhart, Christoph, Junt, Tobias M., Odermatt, Bernhard, Oxenius, Annette, Piali, Luca, Zinkernagel, Rolf M., Hengartner, Hans
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2000
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193195/
https://ncbi.nlm.nih.gov/pubmed/10859340
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