An Instructive Component in T Helper Cell Type 2 (Th2) Development Mediated by Gata-3

Although interleukin (IL)-12 and IL-4 polarize naive CD4(+) T cells toward T helper cell type 1 (Th1) or Th2 phenotypes, it is not known whether cytokines instruct the developmental fate in uncommitted progenitors or select for outgrowth of cells that have stochastically committed to a particular fa...

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Bibliographic Details
Main Authors: Farrar, J. David, Ouyang, Wenjun, Löhning, Max, Assenmacher, Mario, Radbruch, Andreas, Kanagawa, Osami, Murphy, Kenneth M.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2001
Subjects:
Brief Definitive Report
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2193395/
https://ncbi.nlm.nih.gov/pubmed/11238595
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