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Altered Mammary Gland Development in the p53+/m Mouse, a Model of Accelerated Aging

The tumor suppressor p53 is important for inhibiting the development of breast carcinomas. However, little is known about the effects of increased p53 activity on mammary gland development. Therefore, the effect of p53 dosage on mammary gland development was examined by utilizing the p53+/m mouse, a...

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Detalhes bibliográficos
Main Authors: Gatza, Catherine E., Dumble, Melissa, Kittrell, Frances, Edwards, David G., Dearth, Robert K., Lee, Adrian V., Xu, Jianming, Medina, Daniel, Donehower, Lawrence A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234269/
https://ncbi.nlm.nih.gov/pubmed/17996864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2007.10.004
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