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The Combination of Tamoxifen and the Rexinoid LG100268 Prevents ER-Positive and ER-Negative Mammary Tumors in P53-Null Mammary Gland Mice

In pursuit of effective therapeutic agents for the ER-negative breast cancer, we previously demonstrated that bexarotene reduced mammary tumor development by 75% in ErbB2 mice. To further improve the effectiveness of breast cancer prevention, we have now investigated the effects of a combinatorial t...

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Detalhes bibliográficos
Main Authors: Mazumdar, Abhijit, Medina, Daniel, Kittrell, Francis S., Zhang, Yun, Hill, Jamal L., Edwards, David. E., Bissonnette, Reid P., Brown, Powel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3837417/
https://ncbi.nlm.nih.gov/pubmed/22926341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0524
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