Genetics of P450 oxidoreductase: Sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations

P450 oxidoreductase (POR) is an electron-donating flavoprotein required for the activity of all microsomal cytochrome P450 enzymes. We sequenced 5,655 bp of the POR gene in a representative population of 842 healthy unrelated individuals in four ethnic groups: 218 African Americans, 260 Caucasian Am...

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Hlavní autoři: Huang, Ningwu, Agrawal, Vishal, Giacomini, Kathleen M., Miller, Walter L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234213/
https://ncbi.nlm.nih.gov/pubmed/18230729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711621105
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