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Transcriptional Regulation of the Human P450 Oxidoreductase Gene: Hormonal Regulation and Influence of Promoter Polymorphisms

P450 oxidoreductase (POR) is the flavoprotein that acts as the obligatory electron donor to all microsomal P450 enzymes, including those involved in hepatic drug metabolism as well as three steroidogenic P450 enzymes. The untranslated first exon of human POR was located recently, permitting analysis...

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Detalhes bibliográficos
Main Authors: Tee, Meng Kian, Huang, Ningwu, Damm, Izabella, Miller, Walter L.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3082333/
https://ncbi.nlm.nih.gov/pubmed/21393444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2010-0236
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