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Pathways Leading to Phosphorylation of P450c17 and to the Posttranslational Regulation of Androgen Biosynthesis
Cytochrome P450c17 (P450c17) is the single enzyme that catalyzes steroid 17α-hydroxylase and 17,20 lyase activities and hence is the crucial decision-making step that determines the class of steroid made in a steroidogenic cell. Although both activities are catalyzed on a single active site, the rat...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Endocrine Society
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329260/ https://ncbi.nlm.nih.gov/pubmed/18187541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1527 |
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