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Pathways Leading to Phosphorylation of P450c17 and to the Posttranslational Regulation of Androgen Biosynthesis

Cytochrome P450c17 (P450c17) is the single enzyme that catalyzes steroid 17α-hydroxylase and 17,20 lyase activities and hence is the crucial decision-making step that determines the class of steroid made in a steroidogenic cell. Although both activities are catalyzed on a single active site, the rat...

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Detalhes bibliográficos
Principais autores: Tee, Meng Kian, Dong, Qing, Miller, Walter L.
Formato: Artigo
Idioma:Inglês
Publicado em: The Endocrine Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329260/
https://ncbi.nlm.nih.gov/pubmed/18187541
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1527
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