Eradication of disseminated leukemia in a syngeneic murine leukemia model using pretargeted anti-CD45 radioimmunotherapy

We describe the use of pretargeted radioimmunotherapy (PRIT) using an anti–murine CD45 antibody-streptavidin (SA) conjugate followed by radiobiotin to deliver radiation selectively to murine hematolymphoid tissues, which may potentially augment the efficacy and decrease the toxicity of radioimmunoth...

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Detaylı Bibliyografya
Asıl Yazarlar: Pagel, John M., Hedin, Nathan, Drouet, Lacey, Wood, Brent L., Pantelias, Anastasia, Lin, Yukang, Hamlin, Donald K., Wilbur, D. Scott, Gopal, Ajay K., Green, Damian, Appelbaum, Frederick R., Press, Oliver W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2008
Konular:
Neoplasia
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234059/
https://ncbi.nlm.nih.gov/pubmed/18042793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-06-097451
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