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Pretargeted Radioimmunotherapy Using Anti-CD45 Monoclonal Antibodies to Deliver Radiation to Murine Hematolymphoid Tissues and Human Myeloid Leukemia

Radioimmunotherapy (RIT) for treatment of hematological malignancies frequently fails because of disease recurrence. We therefore conducted pretargeted (P)RIT studies to augment the efficacy in mice of therapy using a pretargeted anti-human (h)CD45 antibody (Ab)-streptavidin (SA) conjugate followed...

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書誌詳細
主要な著者: Pagel, John M., Matthews, Dana C., Kenoyer, Aimee, Hamlin, Donald K., Wilbur, Daniel S., Fisher, Darrell R., Gopal, Ajay K., Lin, Yukang, Saganic, Laura, Appelbaum, Frederick R., Press, Oliver W.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613544/
https://ncbi.nlm.nih.gov/pubmed/19118002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2513
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