Pretargeted Radioimmunotherapy Using Anti-CD45 Monoclonal Antibodies to Deliver Radiation to Murine Hematolymphoid Tissues and Human Myeloid Leukemia

Radioimmunotherapy (RIT) for treatment of hematological malignancies frequently fails because of disease recurrence. We therefore conducted pretargeted (P)RIT studies to augment the efficacy in mice of therapy using a pretargeted anti-human (h)CD45 antibody (Ab)-streptavidin (SA) conjugate followed...

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Bibliografiset tiedot
Päätekijät: Pagel, John M., Matthews, Dana C., Kenoyer, Aimee, Hamlin, Donald K., Wilbur, Daniel S., Fisher, Darrell R., Gopal, Ajay K., Lin, Yukang, Saganic, Laura, Appelbaum, Frederick R., Press, Oliver W.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613544/
https://ncbi.nlm.nih.gov/pubmed/19118002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2513
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