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Divalent Cation Sensitivity of BK Channel Activation Supports the Existence of Three Distinct Binding Sites

Mutational analyses have suggested that BK channels are regulated by three distinct divalent cation-dependent regulatory mechanisms arising from the cytosolic COOH terminus of the pore-forming α subunit. Two mechanisms account for physiological regulation of BK channels by μM Ca(2+). The third may m...

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Bibliografske podrobnosti
Main Authors: Zeng, Xu-Hui, Xia, Xiao-Ming, Lingle, Christopher J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234011/
https://ncbi.nlm.nih.gov/pubmed/15738049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200409239
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