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Regulation by Ca(2+) and Inositol 1,4,5-Trisphosphate (Insp(3)) of Single Recombinant Type 3 Insp(3) Receptor Channels: Ca(2+) Activation Uniquely Distinguishes Types 1 and 3 Insp(3) Receptors

The inositol 1,4,5-trisphosphate (InsP(3)) receptor (InsP(3)R) is an endoplasmic reticulum–localized Ca(2+)-release channel that controls complex cytoplasmic Ca(2+) signaling in many cell types. At least three InsP(3)Rs encoded by different genes have been identified in mammalian cells, with differe...

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Detalhes bibliográficos
Main Authors: Mak, Don-On Daniel, McBride, Sean, Foskett, J. Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233662/
https://ncbi.nlm.nih.gov/pubmed/11331354
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