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Inositol 1,4,5-tris-phosphate activation of inositol tris-phosphate receptor Ca(2+) channel by ligand tuning of Ca(2+) inhibition
Inositol 1,4,5-tris-phosphate (IP(3)) binding to its receptors (IP(3)R) in the endoplasmic reticulum (ER) activates Ca(2+) release from the ER lumen to the cytoplasm, generating complex cytoplasmic Ca(2+) concentration signals including temporal oscillations and propagating waves. IP(3)-mediated Ca(...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC28128/ https://ncbi.nlm.nih.gov/pubmed/9861054 |
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