Dynamic and redundant regulation of LRRK2 and LRRK1 expression

BACKGROUND: Mutations within the leucine-rich repeat kinase 2 (LRRK2) gene account for a significant proportion of autosomal-dominant and some late-onset sporadic Parkinson's disease. Elucidation of LRRK2 protein function in health and disease provides an opportunity for deciphering molecular p...

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Bibliografiske detaljer
Main Authors: Biskup, Saskia, Moore, Darren J, Rea, Alexis, Lorenz-Deperieux, Bettina, Coombes, Candice E, Dawson, Valina L, Dawson, Ted M, West, Andrew B
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2233633/
https://ncbi.nlm.nih.gov/pubmed/18045479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-8-102
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