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Neutralization of aspartate residues in the murine inwardly rectifying K(+) channel IRK1 affects the substate behaviour in Mg(2+) block

1. To investigate the molecular basis of the sublevels induced in the outward current during block by intracellular Mg(2+), single-channel currents through inwardly rectifying K(+) (IRK1) channels were studied. 2. cDNA encoding a functional murine IRK1 channel was transfected into COS-1 cells (a Gre...

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Detalhes bibliográficos
Main Authors: Oishi, Keiko, Omori, Koichiro, Ohyama, Hideo, Shingu, Koh, Matsuda, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2231070/
https://ncbi.nlm.nih.gov/pubmed/9660884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.675bj.x
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