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IRK1 Inward Rectifier K(+) Channels Exhibit No Intrinsic Rectification

In intact cells the depolarization-induced outward IRK1 currents undergo profound relaxation so that the steady-state macroscopic I-V curve exhibits strong inward rectification. A modest degree of rectification persists after the membrane patches were perfused with artificial solutions devoid of Mg(...

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Autors principals: Guo, Donglin, Lu, Zhe
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2002
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229529/
https://ncbi.nlm.nih.gov/pubmed/12356855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.20028623
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