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Mechanism of Rectification in Inward-rectifier K(+) Channels

Rectification in inward-rectifier K(+) channels is caused by the binding of intracellular cations to their inner pore. The extreme sharpness of this rectification reflects strong voltage dependence (apparent valence is ∼5) of channel block by long polyamines. To understand the mechanism by which pol...

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Bibliografische gegevens
Hoofdauteurs: Guo, Donglin, Ramu, Yajamana, Klem, Angela M., Lu, Zhe
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217370/
https://ncbi.nlm.nih.gov/pubmed/12642596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200208771
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