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Mechanism of Rectification in Inward-rectifier K(+) Channels
Rectification in inward-rectifier K(+) channels is caused by the binding of intracellular cations to their inner pore. The extreme sharpness of this rectification reflects strong voltage dependence (apparent valence is ∼5) of channel block by long polyamines. To understand the mechanism by which pol...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Rockefeller University Press
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2217370/ https://ncbi.nlm.nih.gov/pubmed/12642596 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200208771 |
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