T cell receptor–induced phosphoinositide-3-kinase p110δ activity is required for T cell localization to antigenic tissue in mice

The establishment of T cell–mediated inflammation requires the migration of primed T lymphocytes from the blood stream and their retention in antigenic sites. While naive T lymphocyte recirculation in the lymph and blood is constitutively regulated and occurs in the absence of inflammation, the recr...

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Autori principali: Jarmin, Sarah J., David, Rachel, Ma, Liang, Chai, Jan-Guo, Dewchand, Hamlata, Takesono, Aya, Ridley, Anne J., Okkenhaug, Klaus, Marelli-Berg, Federica M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2008
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230659/
https://ncbi.nlm.nih.gov/pubmed/18259608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI33267
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