p110γ and p110δ isoforms of phosphoinositide 3-kinase differentially regulate natural killer cell migration in health and disease

The mechanisms that regulate NK cell trafficking are unclear. Phosphoinositide-3 kinases (PI3K) control cell motility and the p110γ and p110δ isoforms are mostly expressed in leukocytes, where they transduce signals downstream of G protein coupled receptors (GPCR) or tyrosine kinase receptors, respe...

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Detalhes bibliográficos
Main Authors: Saudemont, Aurore, Garçon, Fabien, Yadi, Hakim, Roche-Molina, Marta, Kim, Nayoung, Segonds-Pichon, Anne, Martín-Fontecha, Alfonso, Okkenhaug, Klaus, Colucci, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2667007/
https://ncbi.nlm.nih.gov/pubmed/19297623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808594106
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