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Transmembrane Domain Interactions Control Biological Functions of Neuropilin-1

Neuropilin-1 (NRP1) is a transmembrane receptor playing a pivotal role in the control of semaphorins and VEGF signaling pathways. The exact mechanism controlling semaphorin receptor complex formation is unknown. A structural analysis and modeling of NRP1 revealed a putative dimerization GxxxG motif...

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Autors principals: Roth, Lise, Nasarre, Cécile, Dirrig-Grosch, Sylvie, Aunis, Dominique, Crémel, Gérard, Hubert, Pierre, Bagnard, Dominique
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Cell Biology 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230599/
https://ncbi.nlm.nih.gov/pubmed/18045991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E07-06-0625
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