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Single-spanning transmembrane domains in cell growth and cell-cell interactions: More than meets the eye?

As a whole, integral membrane proteins represent about one third of sequenced genomes, and more than 50% of currently available drugs target membrane proteins, often cell surface receptors. Some membrane protein classes, with a defined number of transmembrane (TM) helices, are receiving much attenti...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hubert, Pierre, Sawma, Paul, Duneau, Jean-Pierre, Khao, Jonathan, Hénin, Jélerôme, Bagnard, Dominique, Sturgis, James
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2900628/
https://ncbi.nlm.nih.gov/pubmed/20543559
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