Transmembrane Recognition of the Semaphorin Co-Receptors Neuropilin 1 and Plexin A1: Coarse-Grained Simulations

The cancer associated class 3 semaphorins require direct binding to neuropilins and association to plexins to trigger cell signaling. Here, we address the role of the transmembrane domains of neuropilin 1 and plexin A1 for the dimerization of the two receptors by characterizing the assembly in lipid...

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Detalhes bibliográficos
Main Authors: Aci-Sèche, Samia, Sawma, Paul, Hubert, Pierre, Sturgis, James N., Bagnard, Dominique, Jacob, Laurent, Genest, Monique, Garnier, Norbert
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4032258/
https://ncbi.nlm.nih.gov/pubmed/24858828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0097779
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