Inhibition of primary breast tumor growth and metastasis using a neuropilin-1 transmembrane domain interfering peptide

The transmembrane domains (TMD) in membrane receptors play a key role in cell signaling. As previously shown by us a peptide targeting the TMD of neuropilin-1 (MTP-NRP1), blocks cell proliferation, cell migration and angiogenesis in vitro, and decreases glioblastoma growth in vivo. We now explored t...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Arpel, Alexia, Gamper, Coralie, Spenlé, Caroline, Fernandez, Aurore, Jacob, Laurent, Baumlin, Nadège, Laquerriere, Patrice, Orend, Gertraud, Crémel, Gérard, Bagnard, Dominique
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342376/
https://ncbi.nlm.nih.gov/pubmed/27351129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10101
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