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Post-transcriptional contribution of a cAMP-dependent pathway to the formation of alpha- and beta/gamma-secretases-derived products of beta APP maturation in human cells expressing wild-type and Swedish mutated beta APP.

BACKGROUND: The physiopathological maturation of the beta-amyloid precursor protein can be modulated by effectors targeting a protein kinase C-dependent pathway. These agents increase the recovery of APP alpha, the physiological alpha-secretase-derived product of beta APP processing, and concomittan...

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Detalhes bibliográficos
Main Authors: Marambaud, P., Chevallier, N., Ancolio, K., Checler, F.
Formato: Artigo
Idioma:Inglês
Publicado em: The Feinstein Institute for Medical Research 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230337/
https://ncbi.nlm.nih.gov/pubmed/9932109
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