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Effect of protein kinase A inhibitors on the production of Aβ40 and Aβ42 by human cells expressing normal and Alzheimer's disease-linked mutated βAPP and presenilin 1
1. We previously established that the formation of both α- and β/γ-secretase-derived products generated by human embryonic kidney 293 cells (HEK293) expressing either wild type or mutant βAPP could be stimulated by agonists of the cyclic AMP/protein kinase A pathways. This cyclic AMP-dependent effec...
में बचाया:
| मुख्य लेखकों: | , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
1999
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1565882/ https://ncbi.nlm.nih.gov/pubmed/10205007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0702406 |
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