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High Resolution Imaging Study of Interactions between the 37 kDa/67 kDa Laminin Receptor and APP, Beta-Secretase and Gamma-Secretase in Alzheimer's Disease

Alzheimer's disease (AD) is the most prevalent form of dementia affecting the elderly. Neurodegeneration is caused by the amyloid beta (Aβ) peptide which is generated from the sequential proteolytic cleavage of the Amyloid Precursor Protein (APP) by the β– and γ- secretases. Previous reports re...

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Detalhes bibliográficos
Main Authors: Jovanovic, Katarina, Loos, Ben, Da Costa Dias, Bianca, Penny, Clement, Weiss, Stefan F. T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4074076/
https://ncbi.nlm.nih.gov/pubmed/24972054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100373
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