Llwytho...

Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.

BACKGROUND: An expanded CAG trinucleotide repeat is the genetic trigger of neuronal degeneration in Huntington's disease (HD), but its mode of action has yet to be discovered. The sequence of the HD gene places the CAG repeat near the 5' end in a region where it may be translated as a vari...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Persichetti, F., Ambrose, C. M., Ge, P., McNeil, S. M., Srinidhi, J., Anderson, M. A., Jenkins, B., Barnes, G. T., Duyao, M. P., Kanaley, L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Feinstein Institute for Medical Research 1995
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230005/
https://ncbi.nlm.nih.gov/pubmed/8521295
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!