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Krüppel-like Factor 4 Mediates p53-dependent G(1)/S Cell Cycle Arrest in Response to DNA Damage
The tumor suppressor p53 is required for the maintenance of genomic integrity following DNA damage. One mechanism by which p53 functions is to induce a block in the transition between the G(1) and S phase of the cell cycle. Previous studies indicate that the Krüppel-like factor 4 (KLF4) gene is acti...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229830/ https://ncbi.nlm.nih.gov/pubmed/12427745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M211027200 |
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