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DNA damage and p53-mediated cell cycle arrest: A reevaluation

Most mammalian cells exhibit transient delays in the G(1) and G(2) phases of the cell cycle after treatment with radiation or radiomimetic compounds. p53 is required for the arrest in G(1), which provides time for DNA repair. Recently, a role of p53 in the G(2)/M transition has also been suggested....

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Detalhes bibliográficos
Main Authors: Pellegata, Natalia S., Antoniono, Ronald J., Redpath, J. Leslie, Stanbridge, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26382/
https://ncbi.nlm.nih.gov/pubmed/8986789
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