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Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest.

The tumor suppressor p53 contributes to maintaining genome stability by inducing a cell cycle arrest or apoptosis in response to conditions that generate DNA damage. Nuclear injection of linearized plasmid DNA, circular DNA with a large gap, or single-stranded circular phagemid is sufficient to indu...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Huang, L C, Clarkin, K C, Wahl, G M
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1996
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC39364/
https://ncbi.nlm.nih.gov/pubmed/8643488
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