Sensitivity and selectivity of the DNA damage sensor responsible for activating p53-dependent G1 arrest.
The tumor suppressor p53 contributes to maintaining genome stability by inducing a cell cycle arrest or apoptosis in response to conditions that generate DNA damage. Nuclear injection of linearized plasmid DNA, circular DNA with a large gap, or single-stranded circular phagemid is sufficient to indu...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1996
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC39364/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8643488/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.10.4827 |
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