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On the Molecular Basis of Ion Permeation in the Epithelial Na(+) Channel

The epithelial Na(+) channel (ENaC) is highly selective for Na(+) and Li(+) over K(+) and is blocked by the diuretic amiloride. ENaC is a heterotetramer made of two α, one β, and one γ homologous subunits, each subunit comprising two transmembrane segments. Amino acid residues involved in binding of...

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Bibliografiske detaljer
Main Authors: Kellenberger, Stephan, Hoffmann-Pochon, Nicole, Gautschi, Ivan, Schneeberger, Estelle, Schild, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1999
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229642/
https://ncbi.nlm.nih.gov/pubmed/10398689
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