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On the Molecular Basis of Ion Permeation in the Epithelial Na(+) Channel
The epithelial Na(+) channel (ENaC) is highly selective for Na(+) and Li(+) over K(+) and is blocked by the diuretic amiloride. ENaC is a heterotetramer made of two α, one β, and one γ homologous subunits, each subunit comprising two transmembrane segments. Amino acid residues involved in binding of...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2229642/ https://ncbi.nlm.nih.gov/pubmed/10398689 |
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