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Identification of Amino Acid Residues in the α, β, and γ Subunits of the Epithelial Sodium Channel (ENaC) Involved in Amiloride Block and Ion Permeation

The amiloride-sensitive epithelial Nachannel (ENaC) is a heteromultimeric channel made of three αβγ subunits. The structures involved in the ion permeation pathway have only been partially identified, and the respective contributions of each subunit in the formation of the conduction pore has not ye...

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Main Authors: Schild, Laurent, Schneeberger, Estelle, Gautschi, Ivan, Firsov, Dmitri
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1997
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217053/
https://ncbi.nlm.nih.gov/pubmed/8997662
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