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Identification of Amino Acid Residues in the α, β, and γ Subunits of the Epithelial Sodium Channel (ENaC) Involved in Amiloride Block and Ion Permeation

The amiloride-sensitive epithelial Nachannel (ENaC) is a heteromultimeric channel made of three αβγ subunits. The structures involved in the ion permeation pathway have only been partially identified, and the respective contributions of each subunit in the formation of the conduction pore has not ye...

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Bibliografiske detaljer
Main Authors: Schild, Laurent, Schneeberger, Estelle, Gautschi, Ivan, Firsov, Dmitri
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2217053/
https://ncbi.nlm.nih.gov/pubmed/8997662
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