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A single point mutation in the pore region of the epithelial Na(+) channel changes ion selectivity by modifying molecular sieving
The epithelial Na(+) channel (ENaC) belongs to a new class of channel proteins called the ENaC/DEG superfamily involved in epithelial Na(+) transport, mechanotransduction, and neurotransmission. The role of ENaC in Na(+) homeostasis and in the control of blood pressure has been demonstrated recently...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC22439/ https://ncbi.nlm.nih.gov/pubmed/10097182 |
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