A single point mutation in the pore region of the epithelial Na(+) channel changes ion selectivity by modifying molecular sieving
The epithelial Na(+) channel (ENaC) belongs to a new class of channel proteins called the ENaC/DEG superfamily involved in epithelial Na(+) transport, mechanotransduction, and neurotransmission. The role of ENaC in Na(+) homeostasis and in the control of blood pressure has been demonstrated recently...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.4170 |
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