A single point mutation in the pore region of the epithelial Na(+) channel changes ion selectivity by modifying molecular sieving
The epithelial Na(+) channel (ENaC) belongs to a new class of channel proteins called the ENaC/DEG superfamily involved in epithelial Na(+) transport, mechanotransduction, and neurotransmission. The role of ENaC in Na(+) homeostasis and in the control of blood pressure has been demonstrated recently...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1999
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22439/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10097182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.7.4170 |
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