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Permeability Properties of Enac Selectivity Filter Mutants

The epithelial Na(+) channel (ENaC), located in the apical membrane of tight epithelia, allows vectorial Na(+) absorption. The amiloride-sensitive ENaC is highly selective for Na(+) and Li(+) ions. There is growing evidence that the short stretch of amino acid residues (preM2) preceding the putative...

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Bibliografiske detaljer
Main Authors: Kellenberger, Stephan, Auberson, Muriel, Gautschi, Ivan, Schneeberger, Estelle, Schild, Laurent
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2229513/
https://ncbi.nlm.nih.gov/pubmed/11723161
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