Protein quality control: the who’s who, the where’s and therapeutic escapes

In cells the quality of newly synthesized proteins is monitored in regard to proper folding and correct assembly in the early secretory pathway, the cytosol and the nucleoplasm. Proteins recognized as non-native in the ER will be removed and degraded by a process termed ERAD. ERAD of aberrant protei...

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Detalles Bibliográficos
Main Authors: Roth, Jürgen, Yam, Gary Hin-Fai, Fan, Jingyu, Hirano, Kiyoko, Gaplovska-Kysela, Katarina, Le Fourn, Valerie, Guhl, Bruno, Santimaria, Roger, Torossi, Tania, Ziak, Martin, Zuber, Christian
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2007
Assuntos:
Review
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228381/
https://ncbi.nlm.nih.gov/pubmed/18075753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-007-0366-7
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