Protein quality control: the who’s who, the where’s and therapeutic escapes

In cells the quality of newly synthesized proteins is monitored in regard to proper folding and correct assembly in the early secretory pathway, the cytosol and the nucleoplasm. Proteins recognized as non-native in the ER will be removed and degraded by a process termed ERAD. ERAD of aberrant protei...

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Salvato in:
Dettagli Bibliografici
Autori principali: Roth, Jürgen, Yam, Gary Hin-Fai, Fan, Jingyu, Hirano, Kiyoko, Gaplovska-Kysela, Katarina, Le Fourn, Valerie, Guhl, Bruno, Santimaria, Roger, Torossi, Tania, Ziak, Martin, Zuber, Christian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2007
Soggetti:
Review
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228381/
https://ncbi.nlm.nih.gov/pubmed/18075753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00418-007-0366-7
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