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The Proteasome Is Involved in the Degradation of Different Aquaporin-2 Mutants Causing Nephrogenic Diabetes Insipidus

Mutations in the water channel aquaporin-2 (AQP2) can cause congenital nephrogenic diabetes insipidus. To reveal the possible involvement of the protein quality control system in processing AQP2 mutants, we created an in vitro system of clone 9 hepatocytes stably expressing endoplasmic reticulum-ret...

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Detalhes bibliográficos
Main Authors: Hirano, Kiyoko, Zuber, Christian, Roth, Jürgen, Ziak, Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868181/
https://ncbi.nlm.nih.gov/pubmed/12819016
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