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Oxidative-Nitrosative Stress and Poly(ADP-Ribose) Polymerase (PARP) Activation in Experimental Diabetic Neuropathy: The Relation Is Revisited

Poly(ADP-ribose) polymerase (PARP) activation, an important factor in the pathogenesis of diabetes complications, is considered a downstream effector of oxidative-nitrosative stress. However, some recent findings suggest that it is not necessarily the case and that PARP activation may precede and co...

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Main Authors: Obrosova, Irina G., Drel, Viktor R., Pacher, Pal, Ilnytska, Olga, Wang, Zhong Q., Stevens, Martin J., Yorek, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228259/
https://ncbi.nlm.nih.gov/pubmed/16306359
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