Absence of p21 expression is associated with abnormal p53 in human breast carcinomas.

The p53 tumour-suppressor gene is important in the regulation of cell growth and apoptosis, and loss of functional wild-type activity may be associated with tumour formation and resistance to therapy. Differentiation of functionally normal wild-type protein from mutant or abnormal protein remains di...

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Autors principals: Ellis, P. A., Lonning, P. E., Borresen-Dale, A., Aas, T., Geisler, S., Akslen, L. A., Salter, I., Smith, I. E., Dowsett, M.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 1997
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227991/
https://ncbi.nlm.nih.gov/pubmed/9275025
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