Expression of full-length p53 and its isoform Δp53 in breast carcinomas in relation to mutation status and clinical parameters

BACKGROUND: The tumor suppressor gene p53 (TP53) controls numerous signaling pathways and is frequently mutated in human cancers. Novel p53 isoforms suggest alternative splicing as a regulatory feature of p53 activity. RESULTS: In this study we have analyzed mRNA expression of both wild-type and mut...

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Bibliografiske detaljer
Main Authors: Baumbusch, Lars O, Myhre, Simen, Langerød, Anita, Bergamaschi, Anna, Geisler, Stephanie B, Lønning, Per E, Deppert, Wolfgang, Dornreiter, Irene, Børresen-Dale, Anne-Lise
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2006
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1636663/
https://ncbi.nlm.nih.gov/pubmed/17054774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-5-47
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