Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival

We present a general method for rigorously identifying correlations between variations in large-scale molecular profiles and outcomes and apply it to chromosomal comparative genomic hybridization data from a set of 52 breast tumors. We identify two loci where copy number abnormalities are correlated...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Jain, Ajay N., Chin, Koei, Børresen-Dale, Anne-Lise, Erikstein, Bjorn K., Lonning, Per Eystein, Kaaresen, Rolf, Gray, Joe W.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC35449/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11438741/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.151241198
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