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Quantitative analysis of chromosomal CGH in human breast tumors associates copy number abnormalities with p53 status and patient survival

We present a general method for rigorously identifying correlations between variations in large-scale molecular profiles and outcomes and apply it to chromosomal comparative genomic hybridization data from a set of 52 breast tumors. We identify two loci where copy number abnormalities are correlated...

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Hlavní autoři: Jain, Ajay N., Chin, Koei, Børresen-Dale, Anne-Lise, Erikstein, Bjorn K., Lonning, Per Eystein, Kaaresen, Rolf, Gray, Joe W.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC35449/
https://ncbi.nlm.nih.gov/pubmed/11438741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151241198
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