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Enhanced Cell Death in MeCP2 Null Cerebellar Granule Neurons Exposed to Excitotoxicity and Hypoxia

Rett syndrome (RTT) is associated with mutations in the transcriptional repressor gene MeCP2. Although the clinical and neuropathological signs of RTT suggest disrupted synaptic function, the specific role of MeCP2 in postmitotic neurons remains relatively unknown. We examined whether MeCP2 deficien...

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Bibliografski detalji
Glavni autori: Russell, Juliet C., Blue, Mary E., Johnston, Michael V., Naidu, Sakkubai, Hossain, Mir Ahamed
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227264/
https://ncbi.nlm.nih.gov/pubmed/17997046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.09.076
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