Enhanced Cell Death in MeCP2 Null Cerebellar Granule Neurons Exposed to Excitotoxicity and Hypoxia

Rett syndrome (RTT) is associated with mutations in the transcriptional repressor gene MeCP2. Although the clinical and neuropathological signs of RTT suggest disrupted synaptic function, the specific role of MeCP2 in postmitotic neurons remains relatively unknown. We examined whether MeCP2 deficien...

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Hauptverfasser: Russell, Juliet C., Blue, Mary E., Johnston, Michael V., Naidu, Sakkubai, Hossain, Mir Ahamed
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2227264/
https://ncbi.nlm.nih.gov/pubmed/17997046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2007.09.076
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