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Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1

The Bcl-2 family of proteins regulates apoptosis, the cell death program triggered by activation of certain proteases (caspases). An attractive model for how Bcl-2 and its closest relatives prevent caspase activation is that they bind to and inactivate an adaptor protein required for procaspase proc...

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Detalles Bibliográficos
Main Authors: Moriishi, Kohji, Huang, David C. S., Cory, Suzanne, Adams, Jerry M.
Formato: Artigo
Idioma:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC22270/
https://ncbi.nlm.nih.gov/pubmed/10449754
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