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Telomere restoration and extension of proliferative lifespan in dyskeratosis congenita fibroblasts
Dyskeratosis congenita (DC), an inherited bone marrow failure syndrome, is caused by defects in telomerase. Somatic cells from DC patients have shortened telomeres and clinical symptoms are most pronounced in organs with a high cell turnover, including those involved in hematopoiesis and skin functi...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2225626/ https://ncbi.nlm.nih.gov/pubmed/17381549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2007.00288.x |
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