Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients

Patients with dyskeratosis congenita (DC), a disorder of telomere maintenance, suffer degeneration of multiple tissues1–3. Patient-specific induced pluripotent stem (iPS) cells4 represent invaluable in vitro models for human degenerative disorders like DC. A cardinal feature of iPS cells is acquisit...

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Hauptverfasser: Agarwal, Suneet, Loh, Yuin-Han, McLoughlin, Erin M., Huang, Junjiu, Park, In-Hyun, Miller, Justine D., Huo, Hongguang, Okuka, Maja, dos Reis, Rosana Maria, Loewer, Sabine, Ng, Huck-Hui, Keefe, David L., Goldman, Frederick D., Klingelhutz, Aloysius J., Liu, Lin, Daley, George Q.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3058620/
https://ncbi.nlm.nih.gov/pubmed/20164838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08792
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